Director / producer Ron Howard and producer Brian Grazer have cast international stars to join Tom Hanks in Inferno, the new film in Columbia Pictures’ Robert Langdon series, which has taken in more than $1.2 billion worldwide to date.

The Imagine Entertainment production, which has a screenplay by David Koepp based on the book by Dan Brown, is slated for release on October 14, 2016 and will begin principal photography at the end of April. The project’s executive producers are Dan Brown, Anna Culp, Bill Connor, and David Householter.

Inferno continues the Harvard symbologist’s adventures on screen: when Robert Langdon wakes up in an Italian hospital with amnesia, he teams up with Sienna Brooks, a doctor he hopes will help him recover his memories and prevent a madman from releasing a global plague connected to Dante’s “Inferno.”

Felicity Jones, an Oscar nominee this year for her performance in The Theory of Everything, will star opposite Hanks as Dr. Sienna Brooks.

Irrfan Khan, one of India’s leading actors, best known for his roles in Slumdog Millionaire, Life of Pi, and The Lunchbox, takes the role of Harry Sims, also known as The Provost.

French actor Omar Sy, best known for his work in the French mega-hit The Intouchables, as well as X-Men: Days of Future Past, the upcoming Jurassic World, and John Wells’ upcoming untitled project, will play Christoph Bruder.

Sidse Babett Knudsen, star of the Danish television series “Borgen,” will portray Dr. Elizabeth Sinskey, the head of the World Health Organization. The filmmakers are also in talks with several other internationally recognized actors for major roles.

Michael De Luca and Andrea Giannetti will oversee the project for Columbia Pictures.